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Oakin®

 

 

 
OAKIN® PHARMACOLOGY

The success of Amerx Health Care’s wound and skin care product line is due to the unique properties of Oakin®, an oak extract.

Origin of Oak extract as a medicine

Oak extract has traditionally been used as an antiseptic, anti–inflammatory and astringent agent. The primary application being dermatological – used to treat inflammatory skin conditions, burns, eczema, psoriasis and other forms of dermatitis. Other known uses include treatment of skin conditions due to varicose veins, hemorrhoids, anal fissures and foot odor. Internal uses of oak extract include treatment of acute diarrhea, inflammatory conditions of the mouth and pharyngeal region, as well as urogenital areas.

Actions and properties of Oakin®

Oak extract (Quercus rubra) contains tannins, which include quercitannic acid, catechin, ellagitannin and proanthocyanidin that readily absorb into damaged skin. Tannins are astringent compounds that act locally by precipitating proteins to the wound, decreasing cell membrane permeability and exerting anti–inflammatory and bactericidal properties. The antimicrobial agent is Oakin®, an oak extract containing tannins. Its mode of antimicrobial action is through its ability to inactivate microbial adhesins, enzymes, cell envelope transport proteins. AmeriGel® balances the mix of MMPs and TIMPs in the wound matrix, to stimulate healthy fibroblastic activity and wound healing. Oakin® stimulates PDGF (Platelet Derived Growth Factors) and additional fibroblastic activity, which promotes granulation tissue development. Oakin® is bactericidal (in–vitro) against 51 gram + and - microorganisms.

Oak extract (Quercus rubra) contains tannins, which include quercitannic acid, catechin, ellagitannin and proanthocyanidin that readily absorb into damaged skin. Tannins are highly astringent compounds that act locally by precipitating proteins to the wound, decreasing cell membrane permeability and exerting anti–inflammatory and bactericidal properties.

Oakin® is bactericidal (in–vitro) against 51 gram + and - microorganisms.
The following is an excerpt from the MIC test:

Achromobacter xylosoxidans
Acinetobacter calcoaceticus
Acinetobacter lewoffii
Aeromonas sobria
Alcaligenes faecalis
Candida albicans
Enterobacter aerogenes
Enterobacter cloacae
Escherichia coli
Group D enterococcus
Klebsiella oxytoca
Klebsiella pneumoniae
Listeria monocytogenes
Micrococcus lylae
MRSA
Proteus Mirabilis
Pseudomonas aeruginosa
Pseudomonas alcaligenes
Pseudomonas cepacia
Pseudomonas paucimobilis
Pseudomonas putida
Pseudomonas stutzeri
Rhodotorula rubra
Salmonella choleraesuis
Salmonella enteritidis
Salmonella typhi
Shigella flexneri
Serratia marcesans
Staphylococcus aureus
Staphylococcus epidermidis
Staphylococcus haemolyticus
Staphylococcus hominus
Staphylococcus saprophyticus
Staphylococcus simulans
Streptococcus agalactiae
Streptococcus equisimilis
Streptococcus faecalis
Streptococcus sanguis
Streptococcus uberis
Trichophyton mentagrophytes
VRE

 

Testimonials...   click here for more
Works quite well in minimizing wound drainage following chemical matrixectomy. We’ll continue to use it and expand the use to ulcerations.
Steven H. LeBaron, DPM
Seattle, WA

 

Visit our sister company Sirius Medical Supply.
Sirius Medical Supply Co. was formed to meet the
ever changing needs of the Diabetic community.